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Dr Richard A. DECREAU, Associate Professor Chaire d'excellence - Habilitation


Information
Academic organism : University of Burgundy

Office : B-R27B

Phone: +33 (0)3 80 39 60 63

E-mail : Richard.Decreau(at)u-bourgogne.fr

Education/Research Team : P2DA (Polyamines, Porphyrins, Developments and Applications)

Scientific I.D.

H-index 16

43 papers referenced in Web of Science  , PubMed, ResearchGate

 

American Chemical Society (ACS) Member; Society of Porphyrins and Phthalocyanines (SPP) Member

Biosketch                                                                                                                          The Team's Website


D.O.B. 06.10.1970 (Fr date) 10.06.1970 (US date) in St-Germain-en-Laye (France)

Research Programs


Theranostics: Personnalized Medicine

Porphyrin and Porphyrinoid Science

--> A James P. Collman Pedigree in Dijon

New Medical Imaging Techniques: Unprecedented Contrast Agents

Heme Protein Models

--> Mimicking Nature and Make the Synthetic Assembly function !

 Nanohybrids

 

(1 - 3)


(4)           Yang, Y.; Dey, A.; Decreau, R. A. "Spectroscopic Characterization and Competitive Inhibition Studies of Azide Binding to a Functional NOR Model". Eur J Inorg Chem 2010, 4870-4874.

(5)            Decreau, R. A.; Collman, J. P.; Hosseini, A. "Electrochemical applications. How click chemistry brought biomimetic models to the next level: electrocatalysis under controlled rate of electron transfer". Chem Soc Rev 2010, 39, 1291-1301.

(6)            Collman, J. P.; Ghosh, S.; Dey, A.; Decreau, R. A.; Yang, Y. "Catalytic Reduction of O-2 by Cytochrome c Using a Synthetic Model of Cytochrome c Oxidase". Journal of the American Chemical Society 2009, 131, 5034-+.

(7)            Collman, J. P.; Dey, A.; Yang, Y.; Ghosh, S.; Decreau, R. A. "O-2 reduction by a functional heme/nonheme bis-iron NOR model complex". P Natl Acad Sci USA 2009, 106, 10528-10533.

(8)            Collman, J. P.; Dey, A.; Barile, C. J.; Ghosh, S.; Decreau, R. A. "Inhibition of Electrocatalytic O-2 Reduction of Functional CcO Models by Competitive, Non-Competitive, and Mixed Inhibitors". Inorganic Chemistry 2009, 48, 10528-10534.

(9)            Collman, J. P.; Decreau, R. A.; Lin, H. W.; Hosseini, A.; Yang, Y.; Dey, A.; Eberspacher, T. A. "Role of a distal pocket in the catalytic O-2 reduction by cytochrome c oxidase models immobilized on interdigitated array electrodes". P Natl Acad Sci USA 2009, 106, 7320-7323.

(10)            Collman, J. P.; Decreau, R. A.; Dey, A.; Yang, Y. "Water may inhibit oxygen binding in hemoprotein models". P Natl Acad Sci USA 2009, 106, 4101-4105.

(11)            Collman, J.; Ghosh, S.; Dey, A.; Decreau, R. A. "Using a functional enzyme model to understand the chemistry behind hydrogen sulfide induced hibernation". P Natl Acad Sci USA 2009, 106, 22090-22095.

(12)            Collman, J. P.; Yang, Y.; Dey, A.; Decreau, R. A.; Ghosh, S.; Ohta, T.; Solomon, E. I. "A functional nitric oxide reductase model". P Natl Acad Sci USA 2008, 105, 15660-15665.

(13)            Collman, J. P.; Dey, A.; Yang, Y.; Decreau, R. A.; Ohta, T.; Solomon, E. I. "Intermediates Involved in the Two Electron Reduction of NO to N2O by a Functional Synthetic Model of Heme Containing Bacterial NO Reductase". Journal of the American Chemical Society 2008, 130, 16498-+.

(14)            Collman, J. P.; Dey, A.; Decreau, R. A.; Yang, Y.; Hosseini, A.; Solomon, E. I.; Eberspacher, T. A. "Interaction of nitric oxide with a functional model of cytochrome c oxidase". P Natl Acad Sci USA 2008, 105, 9892-9896.

(15)            Collman, J. P.; Dey, A.; Decreau, R. A.; Yang, Y. "Model studies of azide binding to functional analogues of CcO". Inorganic Chemistry 2008, 47, 2916-2918.

(16)            Collman, J. P.; Decreau, R. A. "Functional biomimetic models for the active site in the respiratory enzyme cytochrome c oxidase". Chemical Communications 2008, 5065-5076.

(17)            Devaraj, N. K.; Decreau, R.; Chidsey, C. E. D.; Collman, J. P. "INOR 83-Mimicking the function of redox enzymes with chemically modified electrodes". Abstr Pap Am Chem S 2007, 234, -.

(18)            Decreau, R. A.; Collman, J. P.; Yang, Y.; Yan, Y. L.; Devaraj, N. K. "Syntheses of hemoprotein models that can be covalently attached onto electrode surfaces by click chemistry". J Org Chem 2007, 72, 2794-2802.

(19)            Collman, J. P.; Yang, Y.; Decreau, R. A. "Synthesis of nitric oxide reductase active site models bearing key components at both distal and proximal sites". Organic Letters 2007, 9, 2855-2858.

(20)            Collman, J. P.; Devaraj, N. K.; Decreau, R. A.; Yang, Y.; Yan, Y. L.; Ebina, W.; Eberspacher, T. A.; Chidsey, C. E. D. "A cytochrome c oxidase model catalyzes oxygen to water reduction under rate-limiting electron flux". Science 2007, 315, 1565-1568.

(21)            Collman, J. P.; Decreau, R. A.; Yan, Y. L.; Yoon, J.; Solomon, E. I. "Intramolecular single-turnover reaction in a cytochrome c oxidase model bearing a Tyr244 mimic". Journal of the American Chemical Society 2007, 129, 5794-+.

(22)            Devaraj, N. K.; Decreau, R. A.; Ebina, W.; Collman, J. P.; Chidsey, C. E. D. "Rate of interfacial electron transfer through the 1,2,3-triazole linkage". J Phys Chem B 2006, 110, 15955-15962.

(23)            Collman, J. P.; Kaplun, M.; Decreau, R. A. "Metal corroles as electrocatalysts for oxygen reduction". Dalton T 2006, 554-559.

(24)            Collman, J. P.; Decreau, R. A.; Sunderland, C. J. "Single-turnover intermolecular reaction between a Fe-III-superoxide-Cu-I cytochrome c oxidase model and exogeneous Tyr244 mimics". Chemical Communications 2006, 3894-3896.

(25)            Collman, J. P.; Wang, H. J. H.; Decreau, R. A.; Eberspacher, T. A.; Sunderland, C. J. "Synthesis and characterization of Rh(III)corroles: unusual reactivity patterns observed during metalation reactions". Chemical Communications 2005, 2497-2499.

(26)            Collman, J. P.; Decreau, R. A. "5,10,15-tris(o-aminophenyl) corrole (TAPC) as a versatile synthon for the preparation of corrole-based hemoprotein analogs". Organic Letters 2005, 7, 975-978.

(27)            Decreau, R. A.; Marson, C. M. "Preparation of 3,17- and 3,20-difluoro- derivatives of the androst-5-ene and pregn-5-ene series". Synthetic Commun 2004, 34, 4369-4385.

(28)            Collman, J. P.; Wang, H. H. J.; Decreau, R.; Sunderland, C.; Eberspacher, T. "Synthesis and characterization of Rh(III) corroles: Unusual reactivity patterns in metallating reactions of free base corroles.". Abstr Pap Am Chem S 2004, 228, U818-U818.

(29)            Collman, J. P.; Decreau, R. A.; Zhang, C. "Synthesis of cytochrome c oxidase models bearing a Tyr(244) mimic". J Org Chem 2004, 69, 3546-3549.

(30)            Collman, J. P.; Decreau, R. A.; Costanzo, S. "Appending a tris-imidazole ligand with a Tyr(244) mimic on the distal face of bromoacetamidoporphyrin". Organic Letters 2004, 6, 1033-1036.

(31)            Barge, J.; Decreau, R.; Julliard, M.; Hubaud, J. C.; Sabatier, A. S.; Grob, J. J.; Verrando, P. "Killing efficacy of a new silicon phthalocyanine in human melanoma cells treated with photodynamic therapy by early activation of mitochondrion-mediated apoptosis". Exp Dermatol 2004, 13, 33-44.

(32)            Decreau, R. A.; Marson, C. M.; Smith, K. E.; Behan, J. M. "Production of malodorous steroids from androsta-5,16-dienes and androsta-4,16-dienes by Corynebacteria and other human axillary bacteria". J Steroid Biochem 2003, 87, 327-336.

(33)            Decreau, R. A.; Collman, J. P. "Corrole synthesis by dipyrromethane-dicarbinol and 2,2 '-bipyrrole condensation". Tetrahedron Lett 2003, 44, 3323-3327.

(34)            Collman, J. P.; Zeng, L.; Decreau, R. A. "Multiple active oxidants in competitive epoxidations catalyzed by porphyrins and corroles". Chemical Communications 2003, 2974-2975.

(35)            Collman, J. P.; Decreau, R. A. "Microwave-assisted synthesis of corroles". Tetrahedron Lett 2003, 44, 1207-1210.

(36)            Marson, C. M.; Decreau, R. A.; Smith, K. E. "Preparation of 3 alpha-Fluoro- and 3 beta-Fluoro derivatives of 5 alpha-androst-16-enes and androsta-5,16-dienes". Synthetic Commun 2002, 32, 2125-2135.

(37)            Barge, J.; Decreau, R.; Sabatier, A. S.; Grob, J. J.; Julliard, M.; Verrando, P. "High photokilling efficacy of bis(cholesteryloxy) silicon phthalocyanine by high cell uptake and early triggering of apoptosis events in melanocytic cells treated with photodynamic therapy". J Invest Dermatol 2002, 118, 1095-1095.

(38)            Barge, J.; Decreau, R.; Julliard, M.; Sabatier, A. S.; Grob, J. J.; Verrando, P. "High killing efficacy of a new silicon phthalocyanine in human melanoma cells treated with photodynamic therapy by early activation of mitochondrion-mediated apoptosis". J Invest Dermatol 2002, 119, 742-742.

(39)            Decreau, R.; Richard, M. J.; Julliard, M. "Photodynamic therapy against achromic M6 melanocytes: phototoxicity of lipophilic axially substituted aluminum phthalocyanines and hexadecahalogenated zinc phthalocyanines". J Porphyr Phthalocya 2001, 5, 390-396.

(40)            Decreau, R.; Chanon, M.; Julliard, M. "Synthesis of aluminum phthalocyanines bearing bulky lipophilic substituents". Synthetic Commun 2000, 30, 2049-2056.

(41)            Decreau, R.; Richard, M. J.; Verrando, P.; Chanon, M.; Julliard, M. "Photodynamic activities of silicon phthalocyanines against achromic M6 melanoma cells and healthy human melanocytes and keratinocytes". J Photoch Photobio B 1999, 48, 48-56.

(42)            Decreau, R.; Julliard, M.; Grob, J. J.; Verrando, P. "Photodynamic therapy against melanoma cells: High efficacy of axially bound silicon phthalocyanines". J Invest Dermatol 1999, 113, 469-469.

(43)            Decreau, R.; Julliard, M.; Giorgi, M. "Bis(epi-globulyloxy)(phthalocyaninato)-silicon, a new photosensitizer for the photodynamic therapy of cancer". Acta Crystallogr C 1999, 55, 1717-1719.

(44)            Decreau, R.; Chanon, M.; Julliard, M. "Synthesis and characterization of a series of hexadecachlorinated phthalocyanines". Inorg Chim Acta 1999, 293, 80-87.

(45)            Viola, A.; Jeunet, A.; Decreau, R.; Chanon, M.; Julliard, M. "ESR studies of a series of phthalocyanines. Mechanism of phototoxicity. Comparative quantitation of O-2 center dot(-) using ESR spin-trapping and cytochrome c reduction techniques". Free Radical Research 1998, 28, 517-532.

(46)            Decreau, R.; Viola, A.; Richard, M. J.; Jeunet, A.; Julliard, M. "Photodynamic therapy: In vivo photosensitizing efficacy of bis(tri-n-hexylsiloxy)silicon phthalocyanine against achromic M6 melanocytes. ESR study of active oxygen intermediates". J Porphyr Phthalocya 1998, 2, 405-414.

(47)            Decreau, R.; Chanon, M.; Julliard, M. "Synthesis of silicon phthalocyanines bearing two cholesterol moieties". Synlett 1998, 375-+.


Academic degree
  • "Photodynamic therapy", Date 11/1998
  • University : Aix-Marseille III University - Hospital Michallon (Grenoble)
  • Advisor : Prof Michel Chanon, Dr Michel Julliard

ICMUB (UMR 5260) - University of Burgundy - Dijon (France)